Bromhexin tablets: instructions for use in adults and children, cough medicine composition

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Bromhexin

Bromhexin tablets: Adult and child use instructions, cough medicine composition width=

Pilot tablets for children white or almost white, round flat-cylindrical with chamfer and rice.

1 tablet.
brromhexine hydrochloride4 mg

Auxiliaries: lactose monohydrate – 80.23 mg, corn starch – 11.54 mg, povidone K25 – 3.46 mg, magnesium stearate – 0.77 mg.

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Pharmacological action

Mucolytic agent with expectorant action. Reduces the viscosity of bronchial secretion by depolarizing acidic polysaccharides contained in it and stimulating secretory cells of the bronchial mucous membrane that produce a secret containing neutral polysaccharides. Bromhexin is believed to contribute to surfactant formation.

Pharmacokinetics

Bromhexin is quickly absorbed from the gastrointestinal tract and undergoes intensive metabolism at “first pass” through the liver. The bioavailability is about 20%. In healthy patients, Cmax in plasma is determined after 1 h.p.

Widely distributed in body tissues. About 85-90% is excreted with urine mainly in the form of metabolites. Bromhexin metabolite is ambroxol.

The binding of bromhexine to plasma proteins is high. T1/2 in the terminal phase is about 12 h.

Bromhexin penetrates through the GEB. In small amounts penetrates placental barrier.

Only small amounts are excreted with urine from T1/2 6.5 h.

Clirence of bromhexine or its metabolites may decrease in patients with severe liver and kidney dysfunction.

Related respiratory tract diseases accompanied by the formation of hard-to-remove viscous secretions: tracheobronchitis, chronic bronchitis with a bronchodilator component, bronchial asthma, cystic fibrosis, chronic pneumonia.

Contraindications

High sensitivity to bromhexin.

Dose

Inside adults and children over 10 years old – 8 mg 3-4 times a day. Children under 2 years of age – 2 mg 3 times a day; 2-6 years of age – 4 mg 3 times a day; 6-10 years of age – 6-8 mg 3 times a day. If necessary, the dose can be increased in adults up to 16 mg 4 times a day, in children – up to 16 mg 2 times a day.

Inhaled in adults – 8 mg, in children over 10 – 4 mg, at the age of 6-10 years – 2 mg. In the age under 6 years – used in doses up to 2 mg. Inhalation is performed 2 times/day.

Therapeutic effect may appear on the 4-6 day of treatment.

Parenteral administration is recommended for treatment in severe cases, as well as in the postoperative period to prevent the accumulation of dense sputum in the bronchi. Enter 2 mg p/k, 2-3 times p/k, or 2-3 times p/day slowly for 2-3 minutes

At the digestive side of the system: dyspeptic phenomena, transient increase of liver transaminases activity in blood serum.

CNS:Headache, dizziness.

Dermatological reactions: Increased sweating, skin rash.

Breathing system side: cough, bronchospasm.

Pharmaceutical interaction

Bromhexin is incompatible with alkaline solutions.

Specific instructions

In case of gastric ulcer as well as in case of indications of gastric bleeding in the history of bromhexine should be used under medical supervision.

With caution in patients with bronchial asthma.

Bromhexin is not used simultaneously with medications containing codeine, as this makes it difficult to cough up liquefied sputum.

It is used in combination preparations of plant origin with essential oils (including eucalyptus oil, anise oil, peppermint oil, menthol).

Pregnancy and lactation

Bromhexin is used in pregnancy and lactation where the expected benefit to the mother exceeds the potential risk to the fetus or child. Highlight it and press Ctrl+Enter.

Source: https://health.mail.ru/drug/bromgeksin/

Cought-tablets

Bromhexin tablets: Adult and paediatric instructions for use, cough medicine composition

Bromgexin cough pills are powerful mucolytic drugs.

This medicine improves the motor skills of the bronchial glands and develops its own secret in the lungs, which helps to reduce the viscosity of sputum clogging the lower respiratory tract.

The drug has a pronounced expectorant effect, promotes mucus excretion and coughing into a productive form.

“Bromhexin” has a low degree of toxicity, which allows it to be well absorbed by the body, both children and adults. In addition, it has little or no effect on the respiratory system's circulation system and has few possible adverse reactions.

Description

Description

Bromhexin cough pills are inexpensive drugs. The average cost of one pack per 10 pieces is 50 rubles. The tablets are coated with a soluble coating, which increases the effectiveness of the drug.

Its cleavage occurs in the intestine, which allows active components to get in large quantities into the systemic blood flow, and then into the lung tissue.

“Bromhexin” is dispensed without a prescription from a doctor and is available for purchase in virtually any pharmacy.

According to the instructions for use, the Bromhexin cough tablets are prescribed for the treatment of an illness of an intensive, unproductive nature, both colds and infectious genesis.

It converts the cough from dry to productive, which is due to its ability to liquefy sputum and provoke its free passage out of the lungs. “Bromhexin expands the bronchial space, purifying and facilitating breathing, improving gas exchange and saturating the bloodstream with more oxygen.

It is this process that enhances the body's immune system and resistance to infectious agents.

Instruction

Before you start taking Bromhexine, you should seek specialist advice. As a rule, the dosage is selected individually, taking into account the patient's condition, age and contraindications, as well as the diagnosis. Standard drug regimens include the following:

Bromhexin cough pills for children from one to two years of age are taken 2 mg each, three times a day. At the age of two to six years, the dosage increases to 4 mg with the same frequency of administration. A child over six years of age is assigned 6-8 mg three times a day. From the age of ten, children are given an adult dose of 8 mg in three dosages per day.

Adult patients are prescribed 8-16 mg of the drug four times a day. This dosage is considered optimal for achieving the therapeutic effect.

It is in this amount that the drug quickly and effectively eliminates inflammation in the respiratory system, brings the secretion function of the bronchi into an active state and stimulates the release of liquefied sputum.

Duration of treatment is no longer than two weeks.

Treatment outcome

Many patients have a positive history of Bromhexin treatment within one week of receiving it. In some cases, the improvement comes on the fourth day.

Prolonged therapy

Physician may decide on a longer course of treatment depending on the patient's condition. Bromgexine is also permitted for preventive purposes, such as stagnation in the postoperative period, when the lungs and other respiratory organs have been surgically manipulated.

Side reactions

Bromhexin cough pills do not have toxic effects on the body, but they do contain a number of possible side effects.

As this way, the body can react to pills as follows:

  • Disturbance of the gastrointestinal tract. Active components of “Bromgexine” can irritate the mucous membrane of the stomach or intestines, which leads to nausea, pain in the abdomen, feeling of heaviness in the subcostal area on the right side, as well as reduced appetite. Vomiting and diarrhoea are also possible, which can cause dehydration.
  • Dizziness. In fact, Bromhexin has no effect on the circulatory system, but against the background of weak cerebral vessels, headaches in the temples and the nape of the head can occur. If this side effect is detected, it is better not to take the drug and to drink an anesthetic. In addition, you need to keep your arterial pressure under control. Even if they increase slightly, you should call an ambulance.
  • Allergic reaction. It appears in the form of rash and itching, bronchial spasm, mucous membrane swelling, and urticaria.

These adverse reactions have been documented in patients treated with Bromhexin in clinical trials. It is especially important to consider the possibility of individual intolerance to the components of the drug.

Analogues

Bromhexin dry cough tablets have a number of analogues in composition and effect. There are also several generics that differ from the original only in name and manufacturer.

Bromhexin Berlin-Chemi cough pills are the most common cough pill produced in Germany.

As well as pills, many drugs are available in the form of solutions and syrups.

If Bromhexina is not available in any of the pharmacy's versions, you can take an analogue. The following products are identical in effect:

  • “Kashnol”. Produced in the form of syrup, the average cost is 170 rubles per package.
  • “Askoril”. Produced in tablet form, as well as in the form of syrup. The price is 300 rubles on average.
  • “Jocet”. The syrup is packaged in bottles of 100 and 200 ml. The price is about 250 rubles.

Cough tablets “Bromhexine” and “Bromhexine Berlin Hemi” are synthetic analogues of the substance that is extracted from the plant called “adatode”. This component is included in natural cough medicines such as Dr. Mom, Travisil and Neutral.

Bromhexin Cough Pill Reviews

The drug is a drug known to more than one generation. He's known a lot of adults since he was a kid. Patients always praise Bromhexin for its speed and efficiency. Many people get rid of even a protracted cough.

Parental note that when using it in a child, after a few days of use, breathing ceases to be heavy and hoarse, sputum is separated much easier and loses its viscosity and density.

The drug is effectively used to treat bronchitis, and it is also safe enough even for young children. Its use is especially relevant in the case of intolerances of analogues. However, there are reviews that describe the drug as ineffective. It doesn't help some patients, even after the treatment.

Patient's opinion of the drug as deficient

One of the disadvantages of Bromhexine is the need for more than a week. In addition, it sometimes caused adverse reactions in the form of dyspeptic disorders, especially in children.

Permitting

Bromhexin is generally considered to be a proven and effective remedy for eliminating dry coughing and alleviating bronchitis and colds. Among other advantages, the drug is affordable, which makes it stand out among similar medicines. However, even such a safe medication is best taken after a specialist's consultation.

Source: http://fb.ru/article/409099/tabletki-ot-kashlya-bromgeksin-instruktsiya-po-primeneniyu-analogi-i-otzyivyi

How to take Bromhexine for coughing

Bromhexine pills: Adult and paediatric instructions for use, cough medicine composition

Bromhexin tablets are a mucolytic drug that is designed to improve the motor skills of the bronchial tree glands and to synthesize your own lung secretion, which reduces the viscosity of the thick sputum that clogs the bronchial space.

The product has a pronounced expectorant effect, facilitates the removal of mucus from the lungs, softens a strong dry cough and facilitates its transition to a productive form. The drug is a low-toxic drug and is therefore well absorbed by patients of different age groups.

Bromgexin pills cost what and whether the cough is dry or wet?

Bromgexin pills cost 45-55 rubles. This package contains 10 tablets coated with a special coating, so that dissolution and absorption of the drug took place not in the stomach, but in the intestines.

This increases the therapeutic effect, and the active ingredients of the drug in a greater volume go into the blood, and with it directly into the lung tissue.

A medicine is dispensed without a special prescription from the prescriber and can be purchased in almost every retail pharmacy.

Bromhexin tablets are designed to treat severe dry coughs of infectious and colds origin.

The drug is able to convert a dry cough into a productive form of cough due to the fact that it can liquefy thick sputum until it starts to come out of the lungs independently during another bronchial spasm.

Through the expansion of the bronchial space, the patient feels that his breathing has become much cleaner and easier, gas exchange is improved and the bloodstream is saturated with a large volume of oxygen. The latter physiological factor plays a key role in increasing the body's immunity and resistance to infectious agents of pulmonary disease.

Provisions

Bromhexin tablets are prescribed by a pulmonologist if a patient is found to have the following lung diseases, namely:

  • acute and chronic bronchitis of colds or of infectious origin, which periodically goes into the stage of exacerbation with coughing and fever;
  • pneumonia with extensive and local inflammatory formations, which is provoked by pneumococcal infection;
  • bronchoectatic disease with abundant purulent content in bronchial sacs (except for infiltrative tissue damage when the lungs are already covered by ulcerative formations);
  • virus inflammation of the upper and lower respiratory tract;
  • bronchial asthma with abundant accumulation of thick mucus.

Physician may prescribe the Bromhexin tablet as a stand-alone medicine or as part of a combination of therapies to achieve maximum healing effect in a short period of time.

Bromhexin administration guidelines

The procedure for taking this medicine for adults and children is set individually. Accordingly, the treatment dosage is also defined as follows:

For children

For children

The child, whose age is from 1 to 2 years old, is shown to take 2 mg of the drug 3 times a day. Children aged 2 to 6 years receive a dosage of 4 mg of medication 3 times a day.

A child aged 6 to 10 years should take 6-8 mg of medication 3 times a day. Children over 10 years of age already receive an adult dose that is within 8 mg. 3-4 times a day.

Therapy for adult men and women includes a dose of 8 to 16 mg of Bromhexin. 4 times a day.

This is the optimal amount of medication that can effectively combat inflammation in the respiratory system, activate the secretion function of the bronchi and accelerate the outflow of sputum until a complete recovery. The duration of a single course of therapy is 10 to 15 days.

In most cases, adults and children show the first signs of a therapeutic effect as early as 4-6 days after the start of the Bromhexin tablets.

At the doctor's insistence, the medication may last longer than the recommended period of time.

It is also allowed to use the drug to prevent congestion in the postoperative period, when the respiratory organs, and especially the lungs, were subjected to surgery.

Side effects

Bromhexin tablets do not have a pronounced toxic effect, but despite this the drug has a number of side effects. They appear in the form of the following atypical reactions of the organism:

  1. Gastrointestinal development. Irritation of the stomach mucosa by the active ingredients of the Bromhexin tablets may cause the patient to feel nausea, abdominal pain, heaviness in the right side of the stomach, lack of appetite. The development of diarrhoea and vomiting with dehydration is not excluded.
  2. Dizziness. Bromhexine has little or no effect on blood circulation, but patients with weak brain vessels may not experience severe painful syndrome in the temples and occipital region of the head. In such cases, it is recommended that you stop taking the pills and take the painkiller. Blood pressure should also be measured. If it is elevated, you should immediately call an ambulance to stabilize your health.
  3. Allergy. Patients prone to allergic reactions may have itching, red rashes on different parts of the body (most commonly rashes on the abdomen), urticaria, bronchial spasm, or swelling of the nasopharynx mucosa.

This is a comprehensive list of possible side effects that have been documented in multiple clinical trials. Also, the individuality factor of each patient's organism should not be discounted.

Other indirect manifestations of not perceiving the medicine are not excluded.

Therefore, the treatment with Bromhexine tablets of pulmonary diseases accompanied by a strong dry cough needs to listen to the behavior of the body.

Source: http://YaDishu.com/drugie-zabolevaniya/tussis/bromgeksin-ot-kakogo-kashlya.html

Referral of Bromhexin cough pills and their analogues

Bromhexin tablets: Adult and child use instructions, cough medicine composition width=

Permanently deaf Bromhexin belongs to the group of drugs with expectorant, mucolytic effect. Available in various forms (tablets, syrup). Patients have almost no questions about the liquid form of the medicine.

What is the purpose of the Bromhexin tablets, the specifics of the use of the instructions – the topics under discussion.

Composition and pharmacological action

Bromhexin tablet contains the main component and a number of additional components. Namely:

  • the role of the active ingredient lies on the hydrochloride of bromhexine;
  • the positions of auxiliary elements are given to lactose monohydrate, sugar, stearic acid, potato starch, microcrystalline cellulose.

Bromhexin is prescribed in tablets for all age groups. Including young children.

Bromhexin is characterized by rapid absorption into the bloodstream through the gastrointestinal walls. Once in the bloodstream, the active substance is transported to the respiratory cells. After the effect, the products of the drug metabolism are excreted with urine (mostly). The effect of the medicine is threefold:

  • mucolytic;
  • expanding;
  • anti-couple (to a lesser extent).

Bromhexine hydrochloride acts on secretory cells (lysosomes) of respiratory mucous tissues. This leads to the active development of surfactant, which restores the normal operation of the lung alveoli.

In addition, the active component of the drug accelerates the process of reducing viscosity, separating sputum and removing it from the body. Available in dosages of 4mg and 8mg of active ingredient per tablet.

Packaging can be 10-100 pieces.

Recipt in Latin

Bromhexin (tablets) is dispensed in pharmacies without a prescription. At the same time, it happens that the doctor writes down a list of drugs for treatment in Latin. Thus, the Latin prescription for an adult patient will look like:

  • Rp. Tab. Bromhexini 0.008;
  • D.t.d. N. 20;
  • S. 2 tablets 3-4 times a day per os.

Kids' dosage in the instructions for use differs from adult dosage. Latin Latin prescription for Bromhexine in baby pills:

  • Rp. Tab. Bromhexini 4mg;
  • D.t.d. N. 50;
  • S. 1 tablet 3 times a day per os.

For a layman it is useful to know what is meant by abbreviations. Here's an Rp. – is “take”, D. t. d. – “let go of that dose”, S. (signa) – “appointment”, Tab. – “pills”, per os – “orally”.

What are these pills for?

Blood liquefaction and sputum removal from the respiratory system to eliminate coughing.

But given the number of diseases accompanied by this symptom, we would like more accurate information: what do the Bromhexin pills do for you? Indications for use are:

According to the instructions for use of the cough tablet Bromhexine is used in bronchopulmonary diseases accompanied by the formation of sputum with high levels of viscosity.

What kind of cough helps?

It's also important to understand what type of coughing Bromhexin tablets are effective against. This information is not fully described in the instructions for use.

These are two main types of symptoms under discussion: dry and wet. The first type manifests itself in:

  • frequent attacks;
  • non detachable sputum;
  • acute sore throat and, sometimes, chest pain.

To eliminate it, it will be necessary to activate the separation of sputum from respiratory tissues. It is also important to ensure that it is quickly deduced.

Wet cough is almost the opposite. Namely:

  • rare attacks;
  • sputum separation at each coughing;
  • easy to spit out mucus.

Depending on the stage of the disease, the color of the sputum varies from transparent to cloudy or reddish red because of the blood inclusions.

Annotation to Bromhexine (tablets) in the instructions for use suggests that the active ingredient stimulates production, viscosity reduction, and sputum separation.

In other words, coughing becomes stronger but more effective. Respiratory system organs are freed from mucus and pathogens/viruses more quickly.

Thus, Bromhexin helps eliminate both types of coughs

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