Creon 10000: Instructions for use in children and adults, composition, analogues of

Creon: Instructions for use, indications, reviews and analogues

Creon 10000: instructions for use for children and adults, composition, analogues of the preparation

Creon is a medicinal product containing pancreatic digestive enzymes. It is prepared from the pancreas of pigs and produced by Abbott.

Creon, an international pharmaceutical company, helps both patients with digestive disorders and healthy people with dietary errors (eating large amounts of fat, starchy and fried food accompanied by abundant feasts during celebrations).

The substance extracted from the pancreas of slaughtered pigs is cleared of various biological impurities, various microorganisms that are carried by pigs, dried and formed into a medicine in the form of pellets or tablets. To the dried pancreatin various substances are added, and from above the special cover which differs firmness to influence of a stomach juice, thereby allowing the preparation to reach a patient's duodenum is put.

Creon 10000 photo

>Creon normalizes process of digestion, after all in its structure those enzymes which take an active part in it contain. The balanced enzyme composition of Creon helps to digest proteins, carbohydrates and fats that come with food, ensuring complete cleavage and assimilation of these substances.

Creon capsules stimulate the production of pancreatic enzymes.

Use for gastrointestinal diseases, pancreatitis, gastroectomy, Schwahman-Daimond syndrome, oral or enteral nutrition recovery.

Release Forms

Capsules 10000, 25000 and 40000 (sometimes mistakenly called tablets).

Creon 10000 contains:
10000 IU lipases, 8000 IU amylases, 600 IU proteases

Creon 25000 contains:
25000 IU lipases, 18000 IU amylases, 1000 IU proteases.

Creon® 40000:
1 capsule contains 400 mg of pancreatin in gastroresistant granules (minimized microspheres ™), which have an enzymatic activity: lipases 40000 units. EP, amylases 25000 EP, proteases 1600 EP, proteases 1600 EP

When the mini-microspheres reach the small intestine, the digestive shell is destroyed, enzymes with lipolytic, amylolytic and proteolytic activity are released, which ensure the cleavage of fats, starchs and proteins.

Creon administration

Creon is used when the exocrine function of the pancreas is insufficient in children and adults due to the lack of exocrine function:

  • Pancreatectomy;
  • Cystic fibrosis;
  • Gastrectomy;
  • Chronic pancreatitis;
  • Pancreatic cancer.

Inside the package there is a must-have been instructions to:

– improve the digestion of food;

-accelerate the digestion of fats and starch in the body;

– intensify the process of splitting fat and starch.

p>In paediatric practice, this drug is administered to children in the case of severe functional impairment of the pancreas due to its lagging behind physiological development.

In addition, Creon is shown for use as an aid in intestinal dysbiosis, accompanied by excessive reproduction of pathogenic bacteria in the small and large intestines and reduced activity of beneficial microflora.

The dosage is based on the individual needs of the patient and depends on the severity of the disease and the composition of the food.

The medicine is recommended during or immediately after meals.

If swallowing is difficult (e.g., in small children or elderly patients), Creon capsules are carefully opened and minimized, the microspheres are added to liquid food that does not need to be chewed or taken with liquids (these opened pellets should not be stored).

Creon's dose is selected individually, depending on nosology, degree of digestive disorder and other factors. In most cases, the initial dosage ranges from 10,000 to 25,000 DU of lipase at each meal.

The maintenance dosage is calculated depending on the nature of the food, the degree of exocrine pancreas insufficiency and averages from 20 thousand to 75 thousand units of lipase during each meal and from 5 thousand units of lipase. Up to 25,000 DU lipase at extra meals.

The standard dosage of Creon for adults is 25,000 to 80,000 DU, i.e. 1-3 Creon capsules 25,000 for meals and half of this dose for snacks.

In case of lack of pancreatic function in different nosologies, the dose is determined according to the results of the steatorea control and the severity of symptoms to maintain 10,000 units of lipase per 1 kg per day.

Pregnant and breastfeeding women are allowed to use Creon only under the supervision of the attending physician, even at a dose of 10000ED. The reason for this is that the pills have not been properly tested in these cases.

Properties of use

Creon® 10,000 has no or little effect on the ability to drive a car and machinery.

This is to be remembered that ethanol worsens digestive processes and adversely affects the breakdown of food, as well as has a huge load on the pancreas, so the use of alcohol containing liquids is contraindicated in the treatment of this organ, including through the use of creon.

In the course of treatment with Creon 10,000, Creon 25,000, Creon 40,000, it is very important to take sufficient liquids, especially during the period of increased loss. Liquid deficiency may cause constipation.

Undesired interactions between Creon and other drugs have not been detected.

This should be remembered that if several drugs are needed, the interval between their use should be at least 5 minutes. This applies to both children and adults.

It is important to use the product with every meal, whether it is a full meal or a snack before dinner: then the absorption of nutrients from the food you eat during the day will be in line with your body's needs.

Side effects Creon:

  • paintings in the epigastric region;
  • constipation;
  • chair changes;
  • diarrhea;
  • nausea,
  • the skin manifestations;
  • hypersensitivity reactions.

As with any other drug, allergies may occur to Creon. It is most often manifested as an allergic rash.


Proceeding from extremely high doses of Creon may lead to hyperuricosemia and hyperuricosea. If you overdose in blood and urine, you may develop a large amount of uric acid salts.

Most overdoses occur with cystic fibrosis. If the doctor diagnosed this diagnosis, the dosage of the drug used should not exceed 10000ED. Otherwise, there may be constrictions of the blind and iliac gut.

Creon Contraindications

Creon is not recommended for patients with hypersensitivity to the drug or its components. In addition, the main contraindications to the use of Creon are acute pancreatitis, as well as chronic pancreatitis in the acute stage.

Also Creon should not be used in the early stages of pancreatitis. When using Creon in children for a long period of time, it is necessary to undergo regular monitoring by a specialist.

The use of Creon during pregnancy and lactation (breastfeeding) is possible only if the expected positive effect of therapy for the mother surpasses the possible risk for the fetus or child, due to the lack of reliable clinical data confirming the safety of pancreatic enzymes in this category of patients.

The duration, dosage and frequency of Creon's pancreatitis therapy you need to talk to your doctor. Creon can be used once a day, on a course and continuously.

Everything depends on the severity of the disease, its course. Sometimes it is necessary to take the doses all the time, but the doses have to be corrected. In remission, reduce, in relapse, increase.

Sometimes you can combine, or replace with other drugs.

The active component of Creon's analogues includes drugs in the form of capsules and tablet forms:

  1. Mesime forte,
  2. Vestal,
  3. Biozyme,
  4. Gastenorm forte,
  5. Microsim,
  6. li>Pancreatine,

  7. Panzim fort,
  8. Panzikam,
  9. Pancitrate,
  10. Unie-Festal,
  11. Hermital.

Also, the medicine can be replaced by a recommendation from the treating gastroenterologist:

  • Pancreazim;
  • Panzital;
  • Panzinorm 10000;
  • Panzinorm Fort 20000;
  • Pancreatin for children.

It is important that the instructions for use of Creon, the price and references to analogues are not and cannot be used as a guideline for the use of similar formulations or actions. All therapeutic prescriptions should be done by a doctor. When replacing Creon with an analogue, it is important to get specialist advice, and it may be necessary to change the course of treatment, dosages, etc.


Analogues are cheaper than Creon, price of Russian and imported substitutes

Creon 10000: instructions for use for children and adults, composition, analogues of the drug
Effective and affordable substitutes for Creon

Creon is a proven enzyme agent used in the treatment of severe gastrointestinal disorders.

It is able to stabilize the digestive system of both adults and children. Despite the many advantages, there is one major disadvantage to this medicine – the considerable cost.

Given the high price tag, it is worth considering the cheaper it is to replace Creon.


Medicament is prescribed in the following cases:

  • Cystic fibrosis;
  • Oncological lesions of the pancreas;
  • Following from pancreatic surgery and removal.


  • Excessive sensitivity to drug components;
  • Acute pancreatitis phase.

Does Creon allow pregnant and lactating women?

Pregnant women are not recommended for this medicine due to the lack of reliable information about its impact on the fetus.

At the same time, in animal experiments, it was found that the drug does not have a detrimental effect on the fetus.

Therefore, women who are preparing to give birth to a child, this pharmaceutical product is prescribed only in extreme cases.

Female breast-feeding members of the weaker sex are not prohibited from taking Creon. Animal studies have shown that breast milk does not contain enzymes that can harm the development of the child.

Probable comorbid reactions

Most cases are treated well. However, abdominal pain, vomiting, emptying difficulties and liquid stools can sometimes occur. Minor skin rashes are allowed.

How do I take Creon?

Instruction for use

The product is taken orally and has sufficient water. Half of the dose should be taken before a meal and the rest of the dose should be taken during the meal. If the patient has difficulty swallowing the capsule, it should be carefully opened, diluted and consumed.

Dose is set individually by the attending doctor. It depends on the complexity of the disease and its course.

In the beginning of therapy, it is recommended to drink 1-2 capsules during the main meal, 1 capsule – during each snack. For effective treatment, you need to take 4 to 15 capsules.

The cost of Creon: the price in the pharmacy

The pharmaceutical product under consideration can be found on the shelves in the pharmacy of all Russian cities. In addition, it is implemented on a special website There its cost (20 capsules in a pack, 10000 units.) starts from 295 rubles (the price – Moscow). The highest price for Creon is 1442 rubles (50 capsules, 40 000 units).

List of inexpensive Russian and imported analogues

Bottom will be shown a table containing similar to the studied pharmaceutical product more affordable substitutes. The list was formed after the collection of information from the most popular online resources engaged in the retail sale of medicines.

Cheaper Analogues than CreonApteka.RUB price in RUB price in RUB
Pangrol (encapsulated form)265276265238
Micrazime (capsules)245256169214
Mezim-Forte 10000 (tablet form)1912011192165
Hermital (caps.)176187179113
Festal (dragee)169181139123
Panzinorm (tablets)td>117149132115
Enzistal (tablets)>104155123100
Penzital (see table.)59616655
Pankreatin (tab.)19202218

Pangrol – (manufacturer Italy/Germany)

Expand to treat chronic pancreatitis, cystic fibrosis, pancreatic cancer. In addition, Pangrol is drunk in the rehabilitation phase after surgeries on this vital organ. Proven efficacy in the treatment of various intestinal infections, improvement of the process of digestion of heavy food.

Appointment application concerns people with acute pancreatitis, allergies to pharma product components.

Sideally possible development of meteorism, vomiting, diarrhea, body rash.

Microasime – (domestic substitute)

Competenten in the fight against pancreatic fibrosis, inflammation and tumors. Recommended for recovery from surgery on this organ.

Is able to correct the digestive processes, stabilize its normal operation. This improves the digestibility of difficult-to-digest foods.

In addition, Micrazim can prepare the patient for an abdominal ultrasound scan.

Not worth treating with this generic in patients with acute pancreatic inflammation or who are not able to tolerate the essential elements of the drug.

Harmful parallel effects are almost non-existent. It's all sorts of allergies, liquid stools, vomiting urges and epigastric pains.

Mezim-Forte 10000- (Russian inexpensive analogue)

A fairly well-known pharmaceutical product has a similar list of indications. These include cystic fibrosis, all sorts of inflammatory processes of the organs responsible for digestion.

How and any medicine Mezim-Forte 10000 has contraindications. Treatment should be refused in case of acute pancreatitis and hypersensitive patients. This is also true for children under three years of age.

Harmful effects can be associated with epigastric pain, nausea.

Hermital – (Indian Generic)

Asian analogue improves digestive processes, digestion of food in case of improper diet, promotes treatment of fibrosis, large gland such as pancreas, various oncological diseases, obstruction of its main channels and gastroporesis.

Hermital is forbidden for people with an allergic reaction to one or another of its components. No more contraindications.

The most frequent side effect is abdominal pain.

Festal – (India)

Manages pancreatitis, the disorders caused by heavy digestion, namely constipation, qualitatively. With the help of Festal, you can prepare the body for an X-ray or ultrasound of the internal organs.

Nelzya take the drug, unlike other considered in this analytical material for those who have hepatitis, jaundice, cholelithiasis, intestinal obstruction, diarrhea, problems with liver function. Age under 3 years is another limitation. Pregnant women are not recommended to use this product.

Side-only irritation of the skin, tearfulness of the eyes, frequent emptying of the intestines, accompanied by moderate colic is possible. The instructions note that prolonged administration may contribute to an increase in uric acid levels in the blood.

Panzinorm – (Slovenia/RF)

Treated pancreatic dysfunction, improved digestive processes, stimulates the gastrointestinal tract in case of malnutrition.

No Panzinorm should be drunk with sensitivity to its composition, exacerbation of pancreatitis and age less than 3 years. To the representatives of the fine sex waiting for the child, experts do not recommend the medicine.

Harmful influences on an organism are not excluded and at reception of this pharmaceutical product: rashes on a skin, a urticaria. In the event of an increase in the dose under threat of the gastrointestinal tract.

Enzistal – (India)

Enzistal is designed to withstand pancreatic dysfunction caused by pancreatic inflammation. Releases the ducts of this organ that have crushed the malignant formation.

Sufficiently alleviates the condition of elderly patients with ailments associated with the organs responsible for the food chain.

With the help of Enzystal, preparatory measures for X-rays and ultrasound of internal organs are carried out.

Categorically contraindicated to people with obstruction of bile and jaundice pathways.

Negative parallel action can have spasmic pains in the epigastric region, nausea, diarrhoea, and allergies (eye lacrimation, rashes, sneezing).

Pensital – (production India)

Also has a wide range of readings. These include cystic fibrosis, abdominal bloating, non-infectious diarrhea, impaired food absorption.

Penzital should not be drunk by people who are negatively sensitive to its active and auxiliary components, acute pancreatitis.

Side effects in the patient when taking this drug are no exception. Most often it's a minor rash, less often a hard chair, abdominal pain, vomiting.

Pancreatine – (the cheapest Russian substitute)

The most affordable analogue of Creon. It has exactly the same indications as all the medicines studied in the article.

It is not uncommon for people who cannot afford to be treated with an expensive medicine.

Pancreatin does a pretty good job of coping with inflammation of the pancreas, liver, intestines, stomach, and other internal organs. It also stabilizes the digestion of foodstuffs.

Parallel harmful effects on the patient and prohibitions of use are identical to all of the above medications.

Conclusion on inexpensive analogues of Creon

The popular German enzyme medicine was considered in this material. Its price is extremely high for ordinary Russian patients.

However, they can get a lot of other, both imported and domestic generics much cheaper.

However, before choosing a drug, you should see a qualified doctor who can determine the optimal drug.


Creon 10000: cheap analogues of the drug, comparison with the original

Creon 10000: instructions for use in children and adults, composition, analogues of the drug width=

Gastrointestinal problems are increasingly haunting large numbers of Russians. Poor nutrition, poor quality of life, regular stress and lifestyle can lead to many diseases ranging from gastritis to stomach cancer.

For the control of discomfort and as a way of preventing serious pathologies in the digestive system, pharmaceutical companies have released many modern and expensive drugs. One of them is Creon 10000.

Active advertising of the drug assures consumers that course of taking these pills can save from the most serious forms of gastrointestinal diseases. However, the manufacturer of the drug wants to get a significant reward for quality assistance – the price of Creon 10000 is more than high.

If there is a need to treat the stomach, but there is no desire to spend all the money saved on medicines, you can give preference to analogues. How to replace Creon 10,000 cheaper, including for the treatment of a child, instructions on the use of drugs and prices will be discussed in the article.

Basic instructions for use

The basis of modern medicine is a well-known substance in the fight against stomach diseases – pancreatin.

He has long been known as one of the most powerful fighters with disorders of the gastrointestinal tract. The action of pancreatin is enhanced by two auxiliary components – macrogol and dimethicone.


It starts with pancreatitis, stomach and pancreatic cancer. Also used in the following cases:

  • partial gastric resection;
  • histectomy;
  • before and after gastrointestinal surgery.


The medicine is available in capsule form. They're in a jar that comes in a cardboard box. The price depends on the number of capsules:

  • for 20 capsules will have to pay within 300 to 560 rubles (depending on the content of the active ingredient);
  • 50 capsules in Russian pharmacies can be purchased for an average of 1550 rubles.

Depending on the duration of treatment, the most appropriate dosage of the drug should be selected. However, in any case, the purchase of the drug will require a significant financial investment.

Since stomach diseases can be a concern not only for adults but also for children, it is necessary to find medicines that can handle the problem gently and safely.

There are cheap analogues of Creon, which can be considered a full replacement for the drug. Of course, their price is much more pleasant.


Provisions. The basis of the drug is pancreatin, reinforced with auxiliary components. Effective against a wide range of stomach diseases:

  • pancreatitis;
  • intestinal infectious diseases;
  • oncological pathologies (stomach cancer, duodenal cancer);
  • Irritated bowel syndrome.

Also used in preparation for examinations, as well as before and after surgery.

The big advantage of the drug is the possibility of treating young patients (age one and older).

Contraindications. It is forbidden to take the medicine in case of exacerbation of the existing disease, as well as in case of individual intolerance to the components of the tablets.

Stoimost. Packaging of tablets in the amount of 20 pieces in Russian pharmacies can be purchased within 25 rubles. For a package containing 60 tablets, you will have to pay 55 rubles.

Comparison with the original. Clear advantage of the analogue over the original – in the cost and in a wider field of application. The original contains pancreatine at the basis of its composition, and the substance can be found directly on the shelves of pharmacies, tens of times cheaper.

Analogue is allowed for use in the treatment of children. It's a great substitute for Creon 10000.


References. The main active ingredient is pancreatine. It's for treatment:

  • various infectious and inflammatory diseases of the stomach and intestines;
  • intestinal obstruction;
  • pancreatitis;
  • diseases of the genitourinary system;
  • liver pathology.

Also assigned to prepare the patient for examinations and surgery. Permitted for the treatment of children from three years of age.

Contraindications. The drug can not be used in case of exacerbation of diseases and intolerance to the components of the drug.

Stability. You can buy the medicine for an average of 80 rubles (20 tablets).

Comparison with the original. Unlike the original, the analogue is not used as therapy for cancer of the gastrointestinal tract

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