Derinate droplets in the nose for children: instructions for use

Derinate droplets in the nose: instructions for use in children and adults, side effects of the drug, analogues

Derinate drops in the nose for children: instructions for use

Derinat is a fairly well-known immunomodulatory agent, which is intended for use in multiple diseases. Derinate is usually produced in several forms.

Derinate is used for intramuscular administration and is used for systemic immunization in various pathologies, including rheumatoid arthritis, COPD, limb atherosclerosis and many others.

In the form of spray, Derinat is used to enhance the immune system of the throat mucous membrane. However, the most common form of the drug is droplets. Derinate is most often used to treat respiratory diseases. In addition, Derinat droplets are widely used for prophylactic purposes.

We will look in more detail at what Derinat droplets are for children, the instructions for use, contraindications and side effects of the drug, and many others.

The form of release of droplets in the nose Derinat

Derinat droplets in the nose are bottle-dropper, containing inside 10 ml of colorless transparent solution. The solution must not contain any visible suspensions. The droplets are odorless and tasteless.

Derinate composition

Sodium deoxyribonucleate is the active ingredient. The concentration of the solution is 0.25%, so each millimeter contains 0.0025 grams of deoxyribonucleate. Sodium chloride is added to this substance. The remainder of the solution is water for injection. Other ingredients and substances are not present in droplets.

Derinat's principle of action – a drop in the nose for children

Derinat's active ingredient differs in its immunomodulatory effect on the body, as it has ability to activate cellular and humoral immunity.

Thanks to this ability, the body's immune response becomes more pronounced in response to the appearance of bacteria, fungi and viruses.

Even though the drug is not able to influence the agents of infection, the droplets help the immune system to fight pathological agents much easier and faster.

As well, Derinate is a reparant because it stimulates the healing and regeneration of the tissue. Particularly effective is the solution in the treatment of trophic ulcers and deep burns.

Drops can accelerate the process of epithelialization of lesions on the skin and mucous membranes.

This explains the high popularity of the drug in surgical area and in ophthalmology.


Derinat Derinat in the nose of children is recommended by paediatricians for acute respiratory infections and simple prophylaxis. In this case, it is used as a monotherapy. Drops can also be used as a supplement to the basic treatment for the following conditions:

  • By sinus;
  • By pharyngitis;
  • and otitis;
  • Pri laryngitis;
  • Adenoid inflammation;
  • Rinitiate.

All these diseases are acute or chronic upper respiratory diseases.

As well as that, droplets are often used for oral inflammation of the mucous membrane of the mouth as well as for ophthalmologic pathologies in which there is an inflammatory process or dystrophy. The drug also has a local application for infecting various wounds, in the presence of trophic ulcer, frostbite, burns and other skin injuries.

As of what age is the use of Derinate allowed? If we talk about the drug in the form of droplets, there are no age-related restrictions. This product is safe even for newborn babies.

Adult instructions

Derinat droplets should be used according to the attached instructions:

  • It's time to sit down and roll the head back or take the
  • Turn the head to the left;
  • Dropping 2-5 droplets into the left nose passage (the number of droplets depends on the destination);
  • Clamp the left nose passage with your finger and make a few circular massaging movements so that the drug is evenly distributed over the mucous membrane of the nostril;
  • Turn the head to the right;
  • Repeat these steps for the right nose passage.

Derinat needs to be buried every 1.5 hours to treat viral respiratory disease, even more often. The drug should be used 3 times a day for preventive purposes.

Derinate for children: Instructions for use

In fact, there is no children's droplet form Derinate. The use of children does not differ significantly from the standard adult procedure. But it is worth noting that the single dose should be less:

  • Children under 2 years of age should be buried 1 drop per nostril;
  • Children from 2 to 10 years of age are recommended to bury 2 drops in each nostril;
  • You can bury 3-4 drops at a time in each nostril older than 10 years.

Newborn and infant guidelines

As mentioned earlier, Derinate droplets are allowed to be used without any age limit. Newborn babies can be buried not only in the nose, but also in the mouth. It stimulates the local immunity of the throat. That's why the droplet form of the drug is more profitable than the spray, because it can not be used for the treatment of newborns.

If we look at the one hand, the child's immunity is in the stage of development, he consistently gets acquainted with the emerging microbial hazards, remembers them, clearly reacts to the bacterial and viral threats. Many doctors believe that this process should not be interfered with. But on the other hand, Derinat droplets are a safe immunomodulatory agent that also has local application.

Instruction for use during pregnancy and lactation

If you read the instructions for use of these drops, you can see that the drug is quickly absorbed after burial. It is also noted that sodium deoxyribonucleate is not able to have a toxic effect on the developing fruit. However, the question of taking droplets during pregnancy is open .

If the general rules are followed, taking any medications during pregnancy is not recommended. But Derinat is one of the safest immunomodulators. Of course, if there is a choice between taking some antibiotics and taking an immunomodulator, it would be more appropriate to give preference to the second option.

But if we talk about the instructions, it does not pay attention to the issue of taking the drug during lactation. That's why it's assumed that you can use Derinat drops during lactation without any worries.

Provisions for use

Derinat droplets are recommended for the following diseases:

  • Virus respiratory diseases;
  • Bacterial acute and chronic respiratory diseases;
  • Eye diseases;
  • Eye diseases;
  • Mouth and gum disease.

Detailed droplets for upper respiratory tract inflammatory diseases are considered in more detail.

Rhinitis from rhinitis

Droplets should be started using when first symptoms of rhinitis appear. The instructions for use state that the drug can stimulate the immune system against both viruses and bacteria. Derinat is usually used as a monotherapy when there is a rhinitis of the viral nature.

But how to distinguish bacterial rhinitis from viral rhinitis? The mucous membrane of the nose tries to get rid of microorganisms from the cavity, starting to secrete a lot of secrets. Bacteria in the nasal cavity are found in most people. Despite this, the number of such bacteria does not exceed a certain limit.

Therefore, in this case it is customary to speak about the opportunistic status of microorganisms. When comparing viruses to bacteria, the former are always pathogenic. If viruses get into the respiratory tract, they immediately get into the mucous membrane cells, where they begin to duplicate.

That's how a sudden onset of runny nose has a viral cause.

The danger of viruses is that they have a suppressive effect on immunity. After the suppression of the immune reaction, the body's defenses begin to decline gradually, which leads to the transition of bacteria from a pathogenic to a pathogenic state.

Despite this, sometimes there is a primary bacterial rhinitis. The weakening of the protective function can occur not only because of the virus, but also for other reasons, including:

  • Smoking;
  • Repooling;
  • Immunodeficiency conditions.

Derinat droplets can also have a local immunostimulatory effect in case of runny nose, which can be caused by any microbial cause. If there is bacterial rhinitis or late onset of treatment, droplets alone will not be sufficient. In such a case, a complex treatment with the use of antibacterial drugs is necessary.

Derinate droplets in maxillary sinusitis

Derinate droplets are not considered as a remedy for maxillary sinusitis. However, it is often used as a prophylactic drug.

It is recommended for individuals who suffer from chronic maxillary sinusitis during the seasonal spike in respiratory disease.

Typically, maxillary sinusitis always develops on the basis of normal runny nose, so it is important to prevent its development.

The composition of complex antibacterial and anti-inflammatory droplet therapy is included as an immune maintenance medicine.

Preventive use of Derinat droplets

Prophylactic use of droplets is recommended during the seasonal increase in respiratory diseases. As a rule, elderly people, children, and people who have been in public for a long time are at risk.

Side effects and overdose

Derinat droplets are generally well tolerated even by children, but there is little risk of further side effects:

  • Discomfort in the nose;
  • Sneezing;
  • Worst and burning in the nose.

These side effects are not particularly dangerous to health. In most cases, they are independent and do not need to cancel the drug treatment.

If we talk about overdose with Derinat droplets, such cases have not yet been registered in medicine.

Interaction with other drugs

If Derinat droplets are used simultaneously with other drugs, there will be strengthening of their therapeutic effect. This is especially true in combination with antibiotics, antiviral drugs and immunostimulants.

This drug can enhance the therapeutic effect of anticoagulants. That's why you have to be very careful with these drug interactions.

Derinat Drop to Nose Analogues

These are analogues of Derinat regarding their therapeutic actions:

  • Sinupret;
  • Drops of Vibrocyl;
  • Sinuforte;
  • Aqua-maris – nasal flushing solution.

But it is worth noting that before taking any analogue, it is necessary to consult a specialist, as the above drugs have contraindications and restrictions on their use.


Derinat: instructions for use

Derinat drops in the nose for children: instructions for use

Treatment by yourself can be harmful to your health.
You should consult your doctor and read the instructions before using.

Active substance: sodium deoxyribonucleate – 25 mg

Auxiliaries: sodium chloride – 10 mg; water for injection – 10 ml


Transparent colorless liquid without foreign inclusions.

The drug activates cellular and humoral immunity. Optimizes specific reactions against fungal, viral and bacterial infections. The preparation stimulates reparative and regenerative processes, normalizes the condition of tissues and organs in vascular dystrophy.

Derinat promotes healing of trophic ulcers of various etiologies. Derinate promotes rapid healing of deep burns, significantly accelerating the dynamics of epithelization. At restoration of ulcerative formations on mucous membranes under the influence of Derinata there is a scarfree recovery.

The drug does not possess teratogenic and carcinogenic actions.


Derinat is quickly absorbed and distributed in organs and tissues with the participation of endolymphatic transport pathway.

In the phase of intense drug intake into the blood redistribution between plasma and blood formulas occurs, in parallel with metabolism and excretion. Derinate is metabolized in the body.

Excreted from the body (in the form of metabolites) partially with faeces, and, to a greater extent, with urine on bi-exponential dependence.


Individual intolerance.

Method of administration and dosage

The drug is administered to children from the first day of life and adults. To prevent acute respiratory viral infections, 2 drops are buried in the nose 2-4 times a day for 1-2 peds.

When symptoms of “colds” appear, the drug is buried in the nose 2-3 drops in each nose every 1-1.5 hours, during the first day; then – 2-3 drops in each nose 3-4 times a day, the duration of the course – 1 month.

Inflammatory diseases of the nasal cavity and sinuses, the drug is buried 3-5 drops in each nasal passage 4-6 times a day. Course duration

– 7-15 days.

In case of oral mucosa diseases, rinses are performed 4-6 times a day (1 bottle 1-2- rinses). Duration of treatment course 5-10 days.

In chronic inflammatory diseases, fungal, bacterial and other infections in gynecology – intravaginal administration with cervical irrigation or intravaginal administration of tampons with the drug, 5 ml per procedure, 1-2 times a day, for 10-14 days.

In severe inflammatory and dystrophic processes in ophthalmology – Derinate is buried in the eyes 2-3 times a day, 1-2 drops each, for 14-45 days.

At post-beam necrosis of a skin and mucous membranes, at long time not healing wounds, burns, frostbite, trophic ulcers of various etiology, gangrene on the affected places impose an application bandage (gauze in two layers) with drawing on it of preparation 3-4 times during day or spend processing of the affected surface by preparation from a nebulizer 4-5 times a day on 10-40 ml (a course of treatment – 1-3 months).

In gangreneous processes under the influence of the drug, spontaneous rejection of necrotic masses in the centers of rejection with restoration of the skin zockeleton is noted. In case of open wounds and burns the analgesic effect is observed.

In case of irritated and damaged nasal mucous membrane caused by acute respiratory viral infections, acute respiratory infections may cause itching and burning sensations.


Overdosing not detected.

Form of release

Solution for outdoor and local use 0.25%. 1 0, 20 ml in glass bottles in package No. 1: drip tray – 10 ml in package No. 1: bottle with nozzle

– atomizer – 10 ml in package No. 1.

Storage conditions

In a dark place at temperatures between +4°C and +20°C. The contents of the opened bottle should be used within two weeks. Keep out of the reach of children.

Standard life

5 years. Do not use after the expiry date indicated on the package.

Derinat analogues, synonyms, and group drugs

Treatment can be harmful to your health.
You should consult your doctor and read the instructions before using.


Derinat drops in the nose: instructions for use. Reviews

Derinate droplets in the nose for children: directions for use

In the fight against infectious disease in the nasopharynx and sinuses, not only medicines aimed at symptomatic treatment are often used, but also to improve immunity. These include Derinat, droplets in the nose that can be prescribed to sick people of all ages, including newborns.

Immunomodulators have a positive effect on cellular and humoral immune defense functions. In particular, they stimulate the activity of B-lymphocytes and T-helpers that recognize antigens and produce antibodies to infectious agents embedded in the human body.

The medicine activates the nonspecific stability of the patient's body. After its introduction, the immune response is strengthened and the inflammation caused by viruses or bacteria is optimized.

Sodium derivate, the active substance, is characterized by a pronounced lymphotropy, which accelerates the process of detoxification by the lymphatic system in patients.

This positive effect allows the drug to be given to those patients who are significantly reduced immunity due to chemotherapy or after radiation therapy.

As well as active components regulate hematopoiesis, that is, normalize the number of blood cells, affecting not only lymphocytes, but also platelets, phagocytes.

What's a Derinat: A description. Indications

The important task of the drug is to stimulate the regeneration of damaged tissues. In addition, it enhances reparative functions, correcting the immune system, increasing the body's resistance.

The composition includes sodium deoxyribonucleate, which is very quickly absorbed by small capillaries when used locally. The lymphatic system then distributes the active substance throughout the body, transporting it to the patient's organs.

Extraction is performed mainly by the genitourinary system, kidneys. Partially excreted together with feces.

Immunostimulant solution is prescribed for various diseases. If they take the intranasal release form for the nose, the monotherapy is aimed at elimination:

  • ORI (including preventive measures during epidemics);
  • Chronical secretory shell infections caused by fungi, bacteria, viruses;
  • Acute rhinitis, sinusitis, etc.

At the same time you can take Sinupret, Rinofluimucil or other tablets/liquids that relieve inflammation, reduce swelling and remove pathological exudates.

Also an immunomodulatory mixture is recommended in case of eye and oral pathologies. Comprehensive medical care is prescribed for the following pathologies:

  • Chronic infections in gynecology;
  • Trophic ulcers, gangrene, nonhealing wounds;
  • Burns, frostbite, necrosis after exposure;
  • Hemorrhoids, gastrointestinal ulcers;
  • Oncology, hematopoiesis disorders;
  • Pulmonary obstruction, tuberculosis, CHD, rheumatoid arthritis, etc.

As of what age can I use an immunomodulator? The instruction says it's suitable for curing even newborn babies.

The drug release form

The drug has a transparent composition, without any shades or foreign inclusions. It is available in several forms:

  • In intramuscular vials of 2 and 5 ml each;
  • In vials for local or outdoor use. Packaged in containers of 10 and 20 ml. The jars are equipped with an I.V. or a sprayer. There are also glass bottles without additional devices for insertion into the nose/ mouth or into the eyes.

Photo derminate

Sodium chloride and water for injection are auxiliaries.

Method of administration and dosage to adults

How to drop the immunomodulatory solution, the attending physician will tell you. The instructions indicate that the number of droplets and the method of use depends on the location of the source of the pathological changes when applied externally or locally.

And for children and adults, the dosage is almost the same. The duration of the course is selected depending on the severity of the pathology.

Preventive treatment of acute respiratory infections is recommended to use antiviral drops in the nose up to four times a day. Two droplets are injected into each nasal passage. During epidemics, it is sufficient to take preventive measures within 7-14 days.

If the patient does show symptoms of acute respiratory viral infections in the course of treatment, then the number of droplets increases to 3, and the number of physical manipulations reduces to one hour, but only the first day. Next, you switch to the standard reception scheme – up to 4 times a day. Duration of the course – 5-30 days.

Diseases of the paranasal sinuses To remove the pathological process in the appendage cavities and on the mucous membranes of the nose, the liquid is buried 3-5 drops in each nostril. You can repeat the introduction 4-6 times a day. One to two weeks of therapy: oral inflammationImmunocorrector is used as a mouthwash.

One bottle is divided into 2-3 uses. You can rinse your mouth up to six times a day. OphthalmologyIf a patient's eyes are inflamed or dystrophic changes appear, the substance is buried up to three times a day. Drops of 1-2 drops per eye.

Continue medical care from two weeks to a month and a half.

For adults, immunocorrector therapy is recommended for more serious pathological changes. It helps to regenerate tissues at hemorrhoids, necroses, infectious diseases in the field of gynecology. Source: nasmorkam.netIf a woman has a fungus or bacterial infection in her sexual system, the solution is recommended for intravaginal irrigation or

A single procedure requires a 5 ml bottle. Treatment continues up to two weeks 1-2 times a day.

Hemorrhoids help microclysms. For this purpose, 15-40 ml of medication is poured into the rectum for up to 10 days.

Necrosis of the skin or secretory membranes, nonhealing wounds, trophic ulcers can also be cured if the system care includes immunostimulant. It's applied with application bandages to the affected areas. It is also possible to spray on wound surfaces. Physiotherapy is performed 4-5 times a day, up to 40 ml of the substance. The course is 1-3 months.

Storage period after opening the ampoule is no more than 14 days. After that time, the solution may lose its properties.

Derinate droplets during pregnancy

For the fertilized egg not to be rejected, immunity is specifically reduced in women after conception. That's why during pregnancy, chronic diseases often become more acute and pathogens are more often infected with pathogens, etc. Can Derinat be used in the nose by women preparing to become mothers?

The instruction says it is contraindicated. Why is that? (Laughs) As already mentioned, the fetus remains in the child-bearing system only because immune cells reduce activity and do not perceive it as an alien body. The immunomodulator's task is to increase immunity, i.e. to reduce the risk of early miscarriage.

In the first trimester of pregnancy, it is particularly dangerous to take immunomodulatory agents because the fetus has not yet attached to the uterine walls and becomes vulnerable to the protective function of the lymphatic system. But at 2 and 3 trimesters, this threat is reduced and can be taken, but only after consultation with a physician.

For pregnant women, it is recommended to conduct a test sample. Start with a single drop of intranasal manipulation.

If no negative reactions are observed and no complications arise, then you can safely use an immunomodulator to eliminate infectious foci.
GV (breastfeeding) should also be consulted with a pediatrician.

Sodium dysoxoribonucleate is absorbed into all organs of the woman, including milk. When breast-feeding, an individual therapeutic regimen can be chosen by the doctor.

Derinat drops in the nose for children

The instruction says that the drug can be prescribed to newborns from the first year of life. The action is designed to improve immunity, so pediatricians most often recommend an immunomodulator for children under a year or older who are exposed to frequent colds.

Studies have shown that any drug form is well tolerated by young patients. Children's derinat has practically no contraindications and is shown in the relief of many diseases associated with inflammatory reactions in the secretory epithelium. Undesirable side effects are very rare.

Droplets for children with sodium deoxyribonucleate are prescribed for the following conditions:


Airway infections (rhinitis, maxillary sinusitis). In order to prevent the child buried 1-3 drops in each nostril. If infected with viruses or bacterial tissue, the amount of the product increases to 5 drops

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