Ciprolet: instructions for use in children and adults, forms of production, antibiotic composition, analogues

Ciprolet: instructions for use, from which the antibiotic is derived, analogues

Cyprolet: instructions for use for children and adults, forms of production, composition of antibiotics, analogues

material:

  • 1 Forms of production and composition
  • 2 Pharmacological action, pharmacodynamics and pharmacokinetics
  • 3 Which is why the antibiotic is prescribed
  • 4 Instructions for use of the Ciprolet for children and adults
  • 5 During pregnancy and lactation
  • 6 Drug interactions and compatibility with alcohol
  • 7 Contraindications, side effects, and overdose
  • 8 Drug analogies

“Ciprolet” is an effective antibiotic that helps to deal with a variety of pathologies. It destroys the bacteria that provoke inflammation, and thus leads to a rapid recovery. In order for the effect of therapy to be fully expressed, it is necessary to strictly follow the instructions attached to the medicine.

Forms of release and composition

The composition of the antibiotic is a chemical compound of ciprofloxacin hydrochloride. It is the drug that has the ability to suppress the activity of bacterial cells.

The medicine is produced in the form of oral tablets and subsequent systemic effects on the body. Every dragee is covered with a film casing for a quick swallowing. One tablet contains 250 mg of active ingredient. In the package can be 10 or 20 pieces.

Another form of release – eye drops. It's a solution with ciprofloxacin in it. 1 ml of liquid drug contains 3 mg of active chemical compound.

Sodium chloride;

  • Sodium chloride;
  • EDERATE DINATORY;
  • Benzoalkonium hydrochloride;
  • Hydric acid.

The basis of the drug is sterile water for injection.

Pharmacological action, pharmacodynamics and pharmacokinetics

Cyprolet tablets are designed to destroy colonies of microbes that live inside the body and cause inflammation.

This is a broad-ranging drug. It works by inhibiting DNA-gyrase in bacteria. As a result, the process of transmission of genetic material during the division of the cell nucleus is disturbed. As a result, a colony of pathogenic microbes is rapidly dying.

The tablets are not appointed immediately. The first thing you need to do is to determine which bacteria have entered the body.

The instruction states that the drug is active in relation to the next list of Gram-negative bacteria:

  • Escherichia coli;
  • Pseudomonas aeruginosa;
  • Shigella spp;
  • Proteus vulgaris;
  • Klebsiella spp;
  • Citrobacter spp.

The medicine is also used to control Gram-positive microbes, in particular some streptococcus and staphylococcus.

Antibiotic enters the bloodstream through the capillaries of the intestinal lint. The compound is then spread evenly over tissues and body fluids. Its maximum concentration is observed in blood neutrophils. The plasma proteins are bound to about 30% of the incoming medication.

Half-decay period lasts 3-5 hours. Its duration is determined by the initial state of the kidneys. The spent substance is mainly excreted with urine and only about 15% with faeces.

That is why the antibiotic is prescribed

All the necessary information about the medicine will be provided by the doctor. Additionally, it is required to study the instructions on how to take “Ciprolet”, what it is usually assigned from, and what the restrictions may be.

The list of indications includes the states provoked by pathogenic activity of bacteria.

So the antibiotic is necessary for infections:

  • bone;
  • muscle;
  • skinned;
  • mucosa;
  • Eye organs;
  • Eye organs

    of the genital tract;

  • of the kidneys and urinary tract;
  • of the GCT;
  • of the respiratory tract;

    of the mouth.

This list allows us to conclude that the tool is multifunctional. Doctors recommend “Ciprolet” for angina, sepsis, peritonitis, cystitis and many other pathologies. Tests are required beforehand to determine whether the existing strain of microorganisms is really sensitive to ciprofloxacin. If the bacteria are resistant, you'll have to choose a different drug.

The Ciprolet Guidelines for Children and Adults

The Ciprolet Antibiotic is taken strictly according to the scheme developed by the treating physician for the particular case. The dose and duration of therapy depend on the diagnosis.

  1. In case of kidney, bladder and duct pathologies, the dose and duration of therapy varies from 250 to 500 mg twice a day. The dose depends on the severity of the symptoms.
  2. The patient needs to take 250 – 500 mg per day to treat respiratory diseases. The dose is divided into two doses.
  3. In gonorrhea it is enough to take a single dose in the chosen dosage (250 – 500 mg).
  4. In case of intestinal infections accompanied by diarrhea, it is enough to take 250 mg per day.
  5. In case of pathologies associated with increased body temperature, prescribe 500 mg twice a day. Total volume – 1000 mg.

Course duration usually varies between 7 – 10 days. It is not advisable to prescribe an antibiotic for less than 5 days, because during this period the colony will not be completely destroyed, and the remaining microbes will be resistant to the drug. For further treatment it is necessary to choose a more powerful and, consequently, more toxic medicine.

It is important. In case of any pathology, the tablets are taken on an empty stomach, not chewing, but swallowing immediately. It is better to do it at the same time at equal intervals, for example, at 8:00 and 20:00 daily.

Pregnancy and lactation

No, when carrying a child, nor during lactation, should the product be taken. If there is a need for emergency treatment, you should consult your doctor and choose a safe for the developing fetus or the child on natural feeding, analogue.

Prophylactic interaction and compatibility with alcohol

Antibiotics cannot be combined with alcohol. “Ciprolet” was no exception.

The tablets are not recommended to be taken at the same time as alcohol, as this combination is fraught with undesirable consequences, including

  • the rapid decline in the effectiveness of the product;
  • an excessive load on the liver, whose cells are involved in the neutralization of alcohol;
  • guaranteed development of side effects.

Pills are undesirable to take in parallel and with some other drugs.

In particular, a joint use with “Cyclosporine” increases the toxic effects on the liver. A similar effect is observed with the use of “Theophylline”. The concentration of this drug in the serum will increase and the half-life of the drug will become too long.

If the patient uses any antacids, the absorption of the antibiotic will be slower and its efficacy will decrease.

The tablets cannot be administered in the following states:

  • pregnancy;
  • breastfeeding;
  • high sensitivity;
  • age under 18 years;
  • pseudomembranous colitis.

Prophysicians also list conditions where the use of pills is possible, but the patient's condition will require increased attention.

This list includes

  • liver pathology;
  • liver failure;
  • atherosclerosis;
  • psychiatric disorders;
  • epilepsy;
  • old age.

The patient may develop side effects while using the antibiotic.

The most common among them:

  • >nausea;
  • diarrhea;
  • inflatation;
  • abdominal pain;
  • the appearance of a rash on the skin.

These signs indicate dysbacteriosis, a condition associated with impaired intestinal microflora balance. The thing is, antibiotics destroy even useful microorganisms that are responsible for normal digestion.

Whatever happens, in parallel with the Ciprolet, physicians prescribe eubiotics such as Linex or Acipol.

The number of other side effects is included:

  • Headaches;
  • Confusion;
  • Fainting;
  • Deafening;
  • tachycardia;
  • erythema;
  • the skin itching;
  • the urine retention;
  • myalgia;
  • general weakness.

All of these symptoms reach their peak intensity when overdosed. In this case, immediate medical attention will be required.

There is no antidote, so the patient will need to rinse the stomach and provide plenty of water.

Medicine taxes

Physician can be assigned to the analogues of “Ciprolet”, which are not inferior to it in effectiveness. The most famous is Ciprofloxacin, which is also available in tablet form.

The number of other similar drugs are included:

  • “Ciprinol”;
  • “Quintor”;
  • “Ciloxane”;
  • “Ecociphol”;
  • “Norfloxacin”.

All of these medicines, like Ciprolet itself, are only available if you have a prescription from your doctor. It is not strictly forbidden to prescribe the tool yourself and use it by instruction.

Source: https://111diet.ru/ciprolet-instrykciia-po-primeneniu-ot-chego-antibiotik-analogi/

Cyprolet A – Instructions for use for children and adults, price and analogues of the medicine, reviews

Cyprolet: instructions for use for children and adults, forms of release, antibiotic composition, analogues

Many leading experts in Russia and the CIS recommend this drug when a powerful antiprotozoic and antibacterial action is required.

If doctors find out about respiratory tract or urinary tract infection and prescribe Ciprolet A – the instructions for use will help to deal with the dosage.

The active ingredients of the drug will help to quickly overcome the disease without causing harm to health. To learn more about this product, read the sequel to the article.

The bactericidal effect of this product has made it a duty instrument for physicians to combat a wide range of infectious diseases. The drug has a low toxicity, so even with prolonged use does not disrupt the operation of internal organs. As for hemodialysis, the active ingredients of Ciprolet A are quickly excreted from the body without accumulating in the tissues.

The main active ingredients of the preparation are tinidazole and ciprofloxacin hydrochloride monohydrate. These components influence bacterial DNA, suppressing the reproduction of harmful microorganisms.

Ciprofloxacin acts on them during their activity and at rest, thus providing a complete bactericidal effect.

The best way to absorb ciprofloxacin and tinidazole is through the use of auxiliary substances:

  • Sodium microscarmellose;
  • Sodium carboxymethyl starch;
  • corn starch;
  • li>microcrystalline cellulose;

  • colloid silica;
  • magnesium stearate;
  • talk.

Form of release

In rare cases, physicians prescribe the drug in the form of eye drops and injectable solutions. Oral tablets Ciprolet A are more widely used. This form of release provides a uniform increase in the concentration of the drug. One pack includes a plastic blister for 10 tablets. It is accompanied by instructions for use.

Antibacterial preparation of fluoroquinolone group has a high degree of lipophilicity. This makes it easy to pass through the outer shell of microorganisms, suppresses intracellular synthesis, and then damages the DNA.

Ciprofloxacin is active against a wide range of microbes of different types because it is a derivative of fluoroquinolone.

Tinidazole effectively manages giardiasis, trichomoniasis, amoebiasis and other severe infections.

In oral administration, both substances are quickly absorbed by the intestines. A slight decrease in absorption may occur if the tablet is taken while eating.

Maximum concentration of ciprofloxacin is achieved after 75-90 minutes. Tinidazole penetrates the mucous membrane for a little longer, up to two hours.

In cerebrospinal fluid, the concentration of active ingredients reaches the same level as in blood plasma.

The use of ciprofloxacin does not cause the development of resistance to other similar agents, not belonging to the group of antibiotics of giraza inhibitors.

Due to this feature the drug is extremely effective against bacteria resistant to penicillins, tetracyclines, aminoglycosides, cephalosporins, etc.e.

Removal of active ingredients from the body is done by means of channel filtration, as well as through the gastrointestinal tract, kidneys, gall bladder (with bile is removed at least 50% of tinidazole).

The antimicrobial agent Ciprolet A is administered to patients suffering from combined bacterial etiology infections caused by microorganisms sensitive to active ingredients. There are several categories of diseases that fall under this description:

  • respiratory tract infections: bronchoectatic disease, bronchitis (acute and chronic in the acute stage), pneumonia;
  • medium and severe infectious diseases of the ENT: maxillary sinusitis, sinusitis, frontitis, maxillary sinusitis, maxillary sinusitis, maxillary sinusitis, maxillary sinusitis, pyelonephritis, cystitis, oral infections: periostitis, periodontitis, acute ulcerative gingivitis.

Contraindications

List of cases in which ciprofloxacin and tinidazole are prohibited:

  • blood depression in the bone marrow;
  • pregnancy;
  • lactation;
  • blood diseases;
  • /li>

  • acute porphyria;
  • age up to 18 years;
  • high sensitivity to imidazole, fluoroquinolone and their derivatives.

In addition, the drug is contraindicated in patients taking Tinidazole. Simultaneous application of these means threatens with drowsiness and pronounced reduction of blood pressure. Patients suffering from cerebral atherosclerosis, mental illness, epilepsy and liver failure should take Ciprolet A with special care.

According to the instructions for use, the drug in the form of tablets should be taken orally while drinking water. The active ingredients of the product penetrate the gastrointestinal tract mucous membranes much faster thanks to the liquid.

Doses of Ciprolet A for oral use are set by the doctor taking into account the severity of the infection and the condition of the patient's kidneys.

In order to avoid too high concentration and difficulties with the elimination of ciprofloxacin, it is recommended that the tablets be taken at regular intervals (usually 12 hours). The basic application diagrams are described below:

  • in gastroenteritis and uncomplicated infectious diseases of the genitourinary system – 250 mg 2 times a day;
  • in acute intestinal infections and diseases in the field of gynecology – 500 mg 2 times a day;
  • in case of prostatitis and complicated diseases of the genitourinary tract – 750 mg 2 times a day;

Patients suffering from diseases such as bacteriemia, peritonitis and sepsis are first prescribed intravenous infusions of Ciprolet A.

The drug enters the body through the blood in the form of liquid, which is immediately exposed to a powerful effect of cyclosporine. The antimicrobial dose has a total healing effect.

Bacterial DNA is destroyed, so that infectious processes begin to retreat.

Side effects and overdose

The instructions for use say that Ciprolet A treatment can cause a number of disorders and disorders in the patient's body. Among them:

  • Digestive system: dryness of the mucous membranes of the oral cavity, reduced appetite, taste of metal in the mouth, vomiting, nausea, abdominal pain, diarrhoea, increased meteorism, hepatonecrosis, hepatitis, cholestatic jaundice (mainly found in patients with liver disease).
  • From the senses: disturbance of sense of smell and taste, hearing loss, tinnitus, visual impairment (Cyprolet A penetrates into the eye fluid).
  • Cardiovascular system: arrhythmia, blood pressure drop, tachycardia.
  • Urinary system side: crystalluria (with reduced diuresis and urine alkaline reaction), hematuria, dizuria, glomerulonephritis, polyuria, albuminuria, interstitial nephritis, urine retention, reduction of renal nitrogen release functions.
  • Allergic reactions: skin rash, itching, petechiae, drug fever, urticariae, shortness of breath, vasculitis, angioedema, eosinophilia, Lyell's syndrome (lack of body fluids).
  • Muscle bone system disorders: arthritis, myalgia, arthralgia, tendovaginitis, tendonitis, tendon diseases (including ruptures).
  • Laboratory indicators: hyperglycemia, hypoprotrotrotrombinemia, hyperbilirubinemia, elevated levels of creatinine in the blood.
  • Other side effects: superinfections (pseudomembranous colitis), asthenia, blood flow to the facial vessels, photosensitization reaction.

Excessive use of cyclosporine leads to an overdose, which is accompanied by symptoms of reversible damage to the urinary system. In some cases, seizures may occur. To get rid of intoxication, you need to induce vomiting and rinse your stomach. Specific antidotes are not available in modern medicine.

In pregnancy

In the period of childbirth, Ciprolet A, like many other antibacterial agents, is prohibited. The drug has a wide range of side effects, which are likely to have a negative impact on the fetus. The safety of ciprofloxacin use during pregnancy is not clinically established, so the consequences may be unpredictable.

According to the instructions for use of Ciprolet A, it should not be administered to patients under 18 years of age.

Interference of the active ingredients in the regulatory and metabolic processes of the child's body can cause a lot of complications.

However, if the severity of the disease is considered critical by the doctor, the drug is used for inpatient treatment from the age of 15 years under strict supervision.

For older patients

Patients of old age are only assigned to Ciprolet A in extreme cases. Older people tend to have many health problems, which significantly increases the likelihood of side effects.

If a doctor does, however, find it necessary to use the drug, you will have to eat, stay on bed rest, and avoid jobs that require increased attention and a high rate of psychomotor response (driving, working with industrial equipment, etc.).

In case of kidney and liver dysfunction

People with severe renal and/or liver failure are treated with special care.

The active ingredients in the drug have a serious impact on the urinary system and other internal organs, so the use of tinidazole and ciprofloxacin can cause serious harm.

In such cases, doctors choose more gentle analogues of Ciprolet to treat kidney and liver infections.

Special instructions

Tsiplet A works effectively, but has a negative impact on many internal organs. In order to minimize the harm to health, the manufacturer of the drug indicated in the instructions for use a number of important nuances that need to be taken into account not only by doctors, but also by patients:

  • Treatment with Ciprolet A may result in cross-allergic symptoms;
  • during the use of the drug it is recommended to avoid direct sunlight;
  • In order to prevent the development of crystalluria, the recommended daily dose should be strictly adhered to;
  • during Ciprolet A treatment it is not recommended to take ethanol in parallel;
  • in case of pain in the joints the treatment should be stopped immediately.

Pharmacological interaction

Clinically established cases of active ingredient entry into a chemical reaction with active ingredients of other drugs:

  • Tsiplet A significantly increases the effect of indirect anticoagulants. Therefore, in order to reduce the risk of bleeding, the drug dose is reduced by 50%.
  • The parallel use of non-steroidal anti-inflammatory agents (excluding acetylsalicylic acid) with Ciprolet A significantly increases the risk of seizures.
  • The drug is compatible with sulfonamides and antibiotics, and when used in combination with them, it is synergistic.
  • Tsiplet A reduces the activity of microsomal oxidation processes in hepatocytes, which increases the concentration of xanthins – caffeine, indirect anticoagulants, etc. In combination with this drug, even a minimal dose of Theophylline can lead to intoxication, so it is not recommended to take them at the same time.
  • The simultaneous use of Warfarin and Ciprolet A from a therapeutic point of view is not advisable. The chemical reaction between the active substances of the drugs leads to a mutual decrease in efficiency.

Cyprolet A – analogues

Patients who follow the doctor's instructions quickly achieve positive results and fully recover. At the same time, there is a category of people who, due to their individual characteristics, are not suitable for this drug. The following analogues can be assigned to them:

  • Safocid;
  • Offlomelid;
  • Netran;
  • Ingalipt-Vial.

Sale and storage conditions

In Russian pharmacies the drug is sold only in the presence of a prescription. Keep the medicine out of the reach of children, protected from moisture and light. The ambient temperature must not exceed 25°C. The shelf life of the pills in such conditions is 36 months.

Price for Ciprolet A

For an average Russian, the cost of the drug is quite acceptable. At the same time, many pharmacies offer cheaper and more efficient alternatives.

According to leading experts, all of them are absolutely safe, so everyone can save money by using an alternative option. The main thing is to study the instructions for use beforehand.

Regarding specific prices, you can find them in the table below:

Name Manufacturer Country Price (in rubles)

/td>India

Tsiplet A
310
NetranRussia200
SafocidIndia650
OflomelidRussia87
Ingalipt-VialRussia65

Replies

Valery, 47 years old


Eugenia, 29 years

When she was in hospital, the doctor prescribed an antiviral. I went to the pharmacy, and my aunt works there. I described my situation to her. Turns out I got the name of the drug wrong. The aunt explained the difference between Ciprolet and Ciprolet A. She bought the package, read the instructions, did everything the doctor said. It helped very quickly.

Alexander, 32 years old

Somewhat was a virus and conjunctivitis at the same time. The doctors prescribed a lot of pills, gave a lot of instructions. The main drug is Ciprolet A. For eyes – regular washing and application of drops. Plus bed rest, no alcohol or unhealthy food. I don't like pills at all, but this antibiotic actually got me back on my feet. Strong drug.

Source: https://sovets.net/13164-ciprolet-a-instrukciya-po-primeneniyu.html

Tsiplet: instructions for use, analogues and reviews, prices in Russian pharmacies

Cyprolet: instructions for use for children and adults, forms of release, composition of antibiotics, analogues

Tsiprolet is an antibacterial drug belonging to the fluoroquinolone group. Used in the treatment of infectious and inflammatory diseases caused by a sensitive microflora.

The active ingredient is ciprofloxacin (an antimicrobial agent of fluoroquinolone group).

In 120 minutes after oral administration, ciprofloxacin is detected in body fluids and tissues at concentrations many times higher than its plasma concentration.

Ciprofloxacin concentration required to suppress bacteria is retained for 0.5 days. The active substance Ciprolet accumulates in organs and tissues, where its content exceeds plasma concentration several times.

Causes disturbances in DNA synthesis, thus disturbing the growth and division of bacteria

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